Correlation of Clinical Parameters and DTI imaging Features in Multiple Sclerosis
نویسندگان
چکیده
Introduction: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that can lead to a continuum of motor deficits including weakness, spasticity, and paresis. Diffusion Tensor Imaging (DTI) can be used in the analysis of MS lesions by tracking water motion in the brain and analyzing connectivity of fiber tracts, which provides more information about the structural composition of the tissue than conventional MRI [1]. The purpose of this study was to investigate the correlation between clinical parameters and DTI imaging features.
منابع مشابه
Evaluation of the relationship between axon injury and clinical symptoms in patients with multiple sclerosis using diffusion tensor MRI imaging
Background: Magnetic resonance imaging (MRI) is a non-invasive imaging technology that shows detailed anatomical and pathological images. It is often used for disease detection, diagnosis, and treatment monitoring, in particular with neurodegenerative diseases, such as Multiple sclerosis (MS), Alzheimer's and amyotrophic lateral sclerosis. However, conventional MRI provides only qualitative inf...
متن کاملDTI Measurements in Multiple Sclerosis: Evaluation of Brain Damage and Clinical Implications
Diffusion tensor imaging (DTI) is an effective means of quantifying parameters of demyelination and axonal loss. The application of DTI in Multiple Sclerosis (MS) has yielded noteworthy results. DTI abnormalities, which are already detectable in patients with clinically isolated syndrome (CIS), become more pronounced as disease duration and neurological impairment increase. The assessment of th...
متن کاملThe Benefits and implementations of Diffusion tensor imaging and Neural Fiber Tractography in Brain Surgery
Background and Aim: The methods for detecting brain activation with fMRI, MRI provides a way to measure the anatomical connections which enable lightning-fast communication among neurons that specialize in different kinds of brain functions. Diffusion tensor imaging is able to measure the direction of bundles of the axonal fibers which are all aligned. Besides mapping white matter fiber tracts,...
متن کاملCLINICAL CORRELATIONS BETWEEN AUDITORY BRAIN STEM RESPONSE AND MAGNETIC RESONANCE IMAGING IN PATIENTS WITH DEFINITE MULTIPLE SCLEROSIS
In an attempt to assess objectively the integrity of the auditory pathways in 30 patients with definite multiple sclerosis (MS), an audiometric evaluation was performed and auditory brainstem responses (ABRs) were obtained. Stressing the auditory system by increasing the stimulation rate showed some enhancement in the identification of MS. 24 (RO%) patients had an abnormal ABR along with c...
متن کاملA Novel Classification Method using Effective Neural Network and Quantitative Magnetization Transfer Imaging of Brain White Matter in Relapsing Remitting Multiple Sclerosis
Background: Quantitative Magnetization Transfer Imaging (QMTI) is often used to quantify the myelin content in multiple sclerosis (MS) lesions and normal appearing brain tissues. Also, automated classifiers such as artificial neural networks (ANNs) can significantly improve the identification and classification processes of MS clinical datasets.Objective: We classified patients with relapsing-r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2009